Home » NEWS » CRISPR-Cas9 heals disease in mice ( mouse)

CRISPR-Cas9 heals disease in mice ( mouse)


When there is no functioning dystrophin, muscle cells get easily damaged due to repeated contractions and relaxations. Eventually, these weakened muscle cells die, leading to the characteristic muscular deterioration linked to DMD.CRISPR-Cas9 heals disease in mice

With progress in the disease, individuals generally males get confined to a wheelchair and eventually develop heart failure because of weakening and dead cardiac muscle.

DMD can be caused by several thousand possible mutations. Most of them are deletions, missing DNA, which leads to the damaged protein. Contrary to this, a promising DMD treatment includes the rational deletion of the dystrophin gene sequence for the production of a so-called microdystrophin.

In mouse models, many microdystrophins have already been constructed and demonstrated to enhance muscle function. Besides this, microdystrophins have also been used in dog models successfully, DMD’s only huge mammalian model. But, in these studies, microdystrophins need to be delivered to the animal, using a virus which can merely deliver genes in a particular size.



Govt Jobs By State

Get Jobs By Category

HELP EACH OTHER: Share Your Thoughts, Queries & Problems With Us Using The Comment Form. We Will Try To Help With The Best We Can!!! You Can Also Help Others With Your Reply & Suggestions Related To This Topic.

Visit Again:- For New Updates On this Topic, You Might Need To Visit This Page Again In Future. So Please Bookmark This Page By Using (CTRL+D On Your Keyboard) & Visit This Page Again Form Your Home Browser.

Stay in Touch:- Don't Forget To Check the Box (Notify Me Of Followup Comments & Posts) To Get New Comments & Reply Directly In Your Mailbox. You Can Also Subscribe To armybharti.in For Latest Jobs In India Using Your Email Address To Get All Jobs & Exams Alerts in your Mailbox.

"armybharti.in is best Place To Discus Jobs & Exams." Download Our Android app:-

Armybharti Android App Download

Leave a Reply

Your email address will not be published. Required fields are marked *